Why do infants rarely experience anaphylactic reactions?

Infants have not yet developed antibodies to allergens, which is a key reason why they rarely experience anaphylactic reactions. The immune system goes through various stages of development, and in the early months of life, infants are often not exposed to the wide range of potential allergens that could trigger such severe responses. Additionally, their immune systems are still forming the specific antibodies needed to recognize and respond to those allergens. Since anaphylaxis is triggered by the release of histamine and other chemicals following the binding of allergens to these pre-formed antibodies, a lack of these antibodies significantly reduces the likelihood of an anaphylactic reaction occurring in infants.

While it is true that infants have an immature immune system, this does not directly correlate with the mechanisms leading to anaphylaxis. Their unique response to medications doesn't specifically contribute to allergic reactions either. Therefore, the primary reason they experience fewer anaphylactic reactions is due to the absence of developed antibodies targeting allergens.