After establishing the airway in a patient who has inhaled a poison, what is the most important management step?

Administering high concentrations of oxygen is the most important management step after establishing the airway in a patient who has inhaled a poison. When a person inhales a toxic substance, their body's ability to utilize oxygen can be compromised due to the interference of the poison with respiratory and circulatory function. Providing high-flow oxygen can help mitigate the effects of hypoxia and enhance the delivery of oxygen to tissues that may be suffering from low oxygen levels.

This step is crucial because many inhaled toxins can cause significant respiratory distress and lead to decreased oxygen saturation in the blood. Supplementing with oxygen can help to displace the toxic gases and increase the oxygen availability in the bloodstream, which can be life-saving.

Other steps such as intubation, monitoring vital signs, or providing fluid resuscitation may be important as well, depending on the specific circumstances of the case. However, they do not address the immediate need for oxygenation in the same direct way that administering high concentrations of oxygen does. After ensuring the patient has adequate oxygenation, a more comprehensive treatment plan can be developed which may include those additional measures.